PANEL TECHNOLOGY

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• BENKit Panel is a novel NGS Medical Device for the molecular profiling of the Hot Spots relevant for the therapy selection in Metastatic Colorectal Cancer and non-small-cell lung carcinoma. BENKit panel is a kit for the analysis of the KRAS, NRAS, BRAF, EGFR and PIK3CA genes through a molecular protocol based on NGS technologies. The kit is validated for somatic analysis (SNPs, indels) of DNA extracted from cancer tissues (fresh, frozen or FFPE) or other body tissues. 

•  BRaCA panel is a CE-IVD kit for the identification of mutations in BRCA1 and BRCA2 genes  through a molecular protocol for Next Generation Sequencing (NGS) technologies on Oxford Nanopore Technologies’ platforms. The kit is validated for germline and somatic analysis (SNVs, CNVs) of DNA extracted from blood samples and tissues (fresh, frozen or FFPE) 

• CFTR panel kit is a CE-IVD kit for the identification of mutations in CFTR gene through a molecular protocol for Next Generation Sequencing (NGS) technologies on Oxford Nanopore Technologies’ platforms. The kit is validated for germline analysis (SNVs, CNVs) of DNA extracted from blood samples and tissues (fresh, frozen or FFPE) 

•  MICROBIOME PLUS panel LONG kit contains all reagents needed for the amplification of bacterial (16S), fungal and mold (18S, ITS1, 5.8S, ITS2) genes and library multiplexing for NGS sequencing using Nanopore platforms. With its long reads-based approach, MICROBIOME PLUS panel LONG kit allows for structural variant detection, metagenomics studies and higher specificity in taxa detection thanksto Nanopore sequencing. This kit can be used in monitoring studies of the human microbiome (e.g., cancer therapy) as well as for environmental screening and approaches (e.g., surface swabs, soil contamination, …) 

•  THALASSEMIA Panel is a novel NGS Medical Device for the molecular profiling of variants causing alpha and beta Thalassemia. Thalassemia is the name for a group of inherited characterized by abnormal hemoglobin production. THALASSEMIA panel is a kit for the analysis of the HBB, HBA1, HBA2, HBD, HBG1, HBG2, HS-40 and LCRB genes through a molecular protocol based on NGS technologies. The kit is validated for germline analysis (SNPs, indels) of DNA extracted from blood samples. 

•  FH Panel is the NGS-bases kit for the molecular profiling of Familial Hypercholesterolemia (FH). FH panel allow complete characterization of 9 genes involved in Familial Hypercholesterolemia and the identification of polygenic FH SNPs and SNPs for the prediction ofstatin response. Familial hypercholesterolemia is a genetic disorder that affects about 1 in 250 people and increasesthe likelihood of having coronary heart disease at a younger age. The importance of an NGS test is reflected in the timeliness of diagnosis and in the possibility of predicting the therapeutic path. FH panel is a kit for the analysis of the FH gene through a molecular protocol based on NGS technologies. The kit is validated for germline analysis (SNPs, indels) of DNA extracted from body tissues (blood or others). 

•  RIDS panel (Respiratory Infectious Diseases Susceptibility) is a kit designed forlarge population screening through a molecular protocol based on NGS technologies. The resulting genetic profile evaluates both genetic variants in the infection pathway (predisposition or protection against infection), and variants of the genes involved in the immune response to infection (predisposition or protection against a worse outcome). The kit is validated for analysis of DNA extracted from different body tissues(blood,saliva, etc. 

•  COVID panel is a CE-IVD kit for the analysis of the entire SARS-CoV-2 genome through a molecular protocol based on NGS technologies. The kit contains all the reagents required for the preparation of specific bidirectional amplicon libraries. The kit is validated for the analysis of cDNA samples obtained from reverse transcription of RNA performed with any commercial kit. 

cDNA input: 30 ng